Sorbitol

DB01638ApprovedInvestigationalSmall moleculeLaxatives

Sorbitol is a product that can be used as a laxative to relieve constipation, and also as a urologic irrigating fluid. May also be used as a pharmaceutical sweetener. A polyhydric alcohol with about half the sweetness of sucrose.

Chemical structure of Sorbitol
Mechanism
Curator reviewed
Primary indication
Used as a non-stimulant laxative via an oral suspension or enema.Curator reviewed · 10 structured indications
Formula / weight
C6H14O6 · 182.1718 g/mol (avg)
First approval
Canada, 2007 · United States, 1978
Also known as
D-glucitol · D-Sorbitol · G-ol · L-Gulitol
Code names
7B5697N · E-420 · FEMA NO. 3029 · NSC-25944
Brand names
  • Cystosol

Resolves to

Compound
UNII506T60A25RCAS50-70-4ChEMBLCHEMBL1682ChEBI17924PubChem5780KEGGD00096
Clinical / RWD
RxNorm9945ATCA06AD18ATCA06AG07ATCB05CX02PharmGKBPA451455
Structure
InChIKeyFBPFZTCFMRRESA-JGWLITMVSA-NSMILESOC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
Targets
O43315AQP9
Transporters
O43315AQP9

What you can answer from here — as of October 03, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action
Listed above
1TransporterSubstrate / inhibitor direction, not just membership
Listed above
1,026Drug interactionsStructured to mechanism, not free text
Sign in
23Clinical trialsPhase, status and sponsor resolved per trial
Sign in
10Structured indicationsCondition, population, route and combination as fields, not prose
Sign in
2ContraindicationsEach with its own population and attribute set
Sign in
53Marketed productsAcross 9 countries and 36 labellers
Sign in
4ATC codesIncluding every combination product, plus 25 drug categories
Sign in
33+ReferencesStructured and connected to the statements they support
Sign in

Which drugs share a target with Sorbitol, and which of those have an active Phase 3 trial?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In