Sorbitol

DB01638ApprovedInvestigationalSmall moleculeLaxatives

Sorbitol is a product that can be used as a laxative to relieve constipation, and also as a urologic irrigating fluid. May also be used as a pharmaceutical sweetener. A polyhydric alcohol with about half the sweetness of sucrose.

Chemical structure of Sorbitol
Mechanism
Curator reviewed
Primary indication
Used as a non-stimulant laxative via an oral suspension or enema.Curator reviewed · 10 structured indications
Formula / weight
C6H14O6 · 182.1718 g/mol (avg)
First approval
Canada, 2007 · United States, 1978
Also known as
D-glucitol · D-Sorbitol · G-ol · L-Gulitol
Code names
7B5697N · E-420 · FEMA NO. 3029 · NSC-25944
Brand names
  • Cystosol

Resolves to

Compound
UNII506T60A25RCAS50-70-4ChEMBLCHEMBL1682ChEBI17924PubChem5780KEGGD00096
Clinical / RWD
RxNorm9945ATCA06AD18ATCA06AG07ATCB05CX02PharmGKBPA451455
Structure
InChIKeyFBPFZTCFMRRESA-JGWLITMVSA-NSMILESOC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
Transporters
O43315AQP9

What you can answer from here — as of September 16, 2026

1TransporterSubstrate / inhibitor direction, not just membership
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1,026Drug interactionsStructured to mechanism, not free text
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23Clinical trialsPhase, status and sponsor resolved per trial
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10Structured indicationsCondition, population, route and combination as fields, not prose
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2ContraindicationsEach with its own population and attribute set
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53Marketed productsAcross 9 countries and 36 labellers
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4ATC codesIncluding every combination product, plus 25 drug categories
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29+ReferencesStructured and connected to the statements they support
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Which other approved drugs treat the same conditions as Sorbitol, and which companies have late-stage candidates in those indications?

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